Good morning and Happy New Year!
I am doing a benchmarking of SV detection methods against simulated genome.
What indels/SNPs ratio should I use when simulating the variants? I read in Dindel paper that they used a 1:9 ratio (1 indel created every 9 SNPs) and in Genetic Variation in an Individual Human Exome that the ratio is 1:7 genome wide (while it is 1:43 in coding regions).
Do you have any recommendation on this?
Best Regards, Pascal