Question: Shrinking fold change and dispersion for RNA-seq data ( DESeq2)
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gravatar for schmilblik
4.3 years ago by
schmilblik20
France
schmilblik20 wrote:

Hello biostars , 

I'm new to rna-seq and i'm trying to introduce myself to DESeq2.

My question is : why do we need to shrink the fold change and dispersion for RNA-seq data ? 

Thanks in advance  

rna-seq deseq2 • 3.1k views
ADD COMMENTlink modified 4.3 years ago by Michael Love1.9k • written 4.3 years ago by schmilblik20
1
gravatar for Michael Love
4.3 years ago by
Michael Love1.9k
United States
Michael Love1.9k wrote:

I'd recommend trying to read the DESeq2 paper from 2014 (we wrote it with non-statisticians in mind), but you might also try this post on another thread:

A: Can someone please explain in simple terms how DESeq2 works?

ADD COMMENTlink written 4.3 years ago by Michael Love1.9k
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