Analysis of genomic data - background reading?

Question

[scchess]

I'm interested to exploit the statistics for genomic data, for example what PLINK does. However, I don't quite follow the statistics in the PLINK paper, because I've never studied it. For example, I have no idea what Hardy-Weinberg conditions is about.

Where can I read more about the topics?

Answer 1

[Devon Ryan]

Hardy-Weinberg equilibrium should be discussed in any genetics text book. Alternatively, read the wikipedia article, which appears pretty good. For what Plink does, have a read through its paper. If you need to learn about the basic stats that it uses then either wikipedia or a statistics book would be helpful (I fully suspect that there's a Coursera class or something like that that would cover basic biostatistics),