Entering edit mode
8.5 years ago
dog.seal6363
•
0
Hello,
I am currently doing a study on the effect of a SNP on a certain population. I was looking at the dbSNP website, and I noticed that the same subjects had different genotypes in different databases. For instance, one person may have a CC genotype while having a GG genotype in another database. Which genotype should I use and why?
Thank you for answering my question.
it's a strand problem. Welcome into the wonderful world of bioinformatics.
You have to find the reference allele and standarize your strands, to say be only the "+" strand. That way you can easily flip any non matching SNPs.
Read on plink