Dear Biostars Portal,
i would like to ask a question regarding the interpretation of two small list of genes that i have acquired through R/Bioconductor and statistical inference. In detail, these lists represent candidates of additive and non-additive effects repsectively, after the use of various combinations of pertubagens in a specific metastatic breast cancer cell line and subsequent microarray gene expression profiling. Because both lists(16 genes and 33 genes) are small to use for input in any functional enrichment methodologies, is there a tool, browser etc that i can specifically search for possible correlations of these genes for (metastatic) breast cancer, and especially and validated/already identified interaction with known drugs(i.e molecular targets)--something like "drug ontologies" ?? Im asking this question, to avoid just get into literature mining, in order to have a more appropriate search on this matter.
Any suggestion or help would be essential !!!
