**190**wrote:

By looking at the numbers below (average depth of DNA sequencing read coverage across transcript regions) I am trying to decide whether for each line V1 and V2 are equal or whether V1 is half of V2 i.e. it looks like the first 12 lines potentially have a ratio of 1:2 (V1:V2) and the rest probably have a ratio closer to 1:1 (V1:V2).

Is there a statistical method of deducing the probability of the ratio being 1:2 (V1:V2)?

I am a novice statistician and have only used methods to find the whether two sets of data have means which are significantly different from each other e.g. Student's t-test, I am unsure how to compare individual numbers, perhaps taking into account the differences in the numbers in the dataset as a whole.

V1 V2

26.4048096192 40.5971943888

42.7286338116 67.3218964442

16.6910523354 28.449634215

25.6696629213 39.7415730337

22.8902439024 35.4198606272

23.4578783151 42.8853354134

30.844304522 47.2364052662

21.3841059603 45.9911699779

26.9329608939 53.3240223464

25.6696629213 39.7415730337

22.8902439024 35.4198606272

23.4578783151 42.8853354134

48.4988523336 42.5401683244

66.9087759815 56.2771362587

30.9506517691 44.8621973929

41.0501567398 36.207523511

14.7519747235 11.4992101106

98.5691964286 86.9235491071

112.394004283 109.324411135

77.6472694718 70.7502238138

16.791973792 15.1638001638

47.6559691913 40.216944801

52.3489795918 48.362244898

83.0362537764 78.9007337074

47.7375565611 42.4809954751

85.6609654124 78.0877993158

85.1274038462 90.8990384615

153.882743363 126.502212389

99.50558109 93.8778726198

66.8800773694 58.5222437137

30.3466026081 29.2868908717

55.5277078086 52.7877833753

81.8555408971 74.9525065963

86.95684803 82.0356472795

85.0009587728 81.0872483221

203.495197439 135.008537887

70.7687908497 74.9027777778

87.9617065557 82.0097814776

84.094017094 83.5337132004

30.3687707641 45.0897009967

93.0515653775 90.2780847145

80.6575875486 79.2879377432

21.380224261 19.6819571865

40.7149700599 40.7023952096

103.873167982 94.3038331454

44.9216677195 44.0650663298

22.7315377932 19.5851433536

31.1595383571 25.9450101833

144.497706422 142.811926606

80.0854621458 70.4226660474

80.4943127962 72.2900473934

18.4689213894 20.7294332724

123.254526092 126.424920128

26.4048096192 40.5971943888

42.7286338116 67.3218964442

89.939923539 86.7706171491

74.0379020287 67.8980702622

84.1919866444 74.8113522538

**17k**• written 5.0 years ago by jomaco •

**190**