Question: HHpred threading or homology ?
gravatar for modmod
5.3 years ago by
modmod0 wrote:

Hi, I can't figure out if HHpred should be considered as a trading tool (like I-Tasser) or a homology detection tool (like Psi-Blast).

Let's say, I build a model using an HHpred template, it's homology modelling or threading?

Thanks in advance

sequence alignment • 1.2k views
ADD COMMENTlink modified 2.4 years ago by Biostar ♦♦ 20 • written 5.3 years ago by modmod0

It is not a threading tool like ITasser.

It is closer to Psi-Blast conceptually, but you should read up on what a Hidden Markov Model is doing with the data to really understand the concept.

ADD REPLYlink written 2.4 years ago by Joe18k
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