Entering edit mode
8.4 years ago
mkrause
▴
30
Hello Community.
I am facing problems with mappability after doing MNase ChIP-Seq.
Somehow I enrich for multimapper fraction in Seq results.
The quality and complexity of the reads are fine, but multi mappers are overrepresented (70-80%).
I wonder whether this could be due to not-fitting library prep.
Does anyone has experience on which library prep kit fits best for MNase experiments?
Thanks