Is it possible to search for orthologs/inparalogs only for specific sequences in the query genome?
I'm aware that searching for orthologs requires complete proteomes. I would like to avoid a step where OMA calculates all-versus-all sequence comparisons of all proteins from query and subject genomes. In fact, I don't have to BLAST all proteins in a proteome when I'm interested only in one protein. I was wondering whether OMA can be used this way? For example, Reciprocal Smallest Distance (RSD) approach lets users to find orthologs for specific sequences in the query genome.