Tilled regression analysis package (TRAP)
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8.3 years ago
toyan.j.p ▴ 30

Hi,

  1. I would like to know how analysis with TRAP is different from linear regression for quantitative traits? I tried both with a data of 49 variants in a sample of 50 individuals. Is it advisable to do TRAP when you are analysing only cisQTLs? I tried both and there are differences in results obtained, though some are common
  2. Another query is in the final results from TRAP, there is a section lists P values-what are they?

e.g.: 8.207e-08, 2.491e-04 and 6.771e-04

PREDICTORS IN SELECTED SET (MAIN EFFECTS ONLY):
                                     ______Single_______    __Genome-selected__
Predictor   Chr   Position  Tile    /     N  P          \  /     N  P          \
================================================================================
                                                                50  8.207e-08
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
snp1  X  136494594  A6           50  2.491e-04              6.771e-04
snp2  X  136499412  A25          50  1.024e-02              2.001e-03
snp3  X  136500515  A29          50  1.859e-04              7.932e-03
snp4  X  136523847  A45          50  7.188e-03              3.646e-03

FITTED MODEL (MAIN EFFECTS ONLY):

serum =
              (   6.20248)
            + (   24.9027) x snp1
            + (   15.7717) x snp2
            + (   10.3505) x snp3
            + (   13.0561) x snp4

What are the terms in parenthesis? Are these beta values?

Thanks in advance for any help

Regards

Toyanji

TRAP • 1.4k views
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