Dear community members,
I would like to ask you for your suggestions for selecting a test to detect signatures of selection in the following mouse model:
We have three groups: animals exhibiting trait A, trait B and controls. These animals were selected over the last 4 decades (controls were mated randomly and do not show any of the traits). That is total 170 generations (~4 generations per year).
We want to detect the genomic signatures of selection for trait A and B.
I am new in population genomics, but according to this paper (http://www.ncbi.nlm.nih.gov/pubmed/21218185), showing a decision tree (fig 1). I should apply a the Fst and a Linkage 'Disequilibrium test, given that the time scale would be short (40 years, 170 generations) and there are multiple populations.
Could you corroborate if this is the correct approach?