Question: Determining sample size in a miRNA experiment
0
gravatar for mgab
3.3 years ago by
mgab40
Germany
mgab40 wrote:

I would like to conduct a miRNA experiment using high-throughput. I would like to determine the appropriate sample 

size to use. There are microarray methods to determine sample size. Is there any method for determining sample size in miRNA? Thank you.

m

mirna sample size genome • 1.3k views
ADD COMMENTlink modified 3.3 years ago • written 3.3 years ago by mgab40
2
gravatar for Devon Ryan
3.3 years ago by
Devon Ryan89k
Freiburg, Germany
Devon Ryan89k wrote:

Yes, there's scotty and the bioconductor RNASeqPower package. In general, though, you end up selecting a published dataset and hoping that yours is similar. So how reliable this is comes down to how similar the effect sizes are. Realistically speaking, most people decide how much they want to spend first and then figure out how many samples they can afford (and if you can afford a LOT of samples then just do things the right way with a pilot project).

ADD COMMENTlink written 3.3 years ago by Devon Ryan89k
0
gravatar for mgab
3.3 years ago by
mgab40
Germany
mgab40 wrote:

Thanks Devon. Much appreciated. m

ADD COMMENTlink written 3.3 years ago by mgab40
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