Pathway enrichment for Copy Number Alterations (CNA)
1
1
Entering edit mode
8.1 years ago
Chirag Nepal ★ 2.4k

Hi all,

I used genome music to determine enriched pathways in SNV. Are there any tools to do enriched pathways analysis in CNA.

Thanks!

Genome-Music CNV CNA • 2.3k views
ADD COMMENT
0
Entering edit mode
8.1 years ago

It's a difficult problem, because a typical arm-level CNA can encompass hundreds or thousands of genes. If you have a cohort, you might try running something like GISTIC to identify the focal peaks of CN, and then run that much smaller set of genes through enrichment analysis.

ADD COMMENT
0
Entering edit mode

Thanks Chris !

I have done the same. I wanted to know if there were some better ways to do.

ADD REPLY

Login before adding your answer.

Traffic: 2647 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6