The main idea of this technology is introduced in this paper:
Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution
It seems can give better result than ChIP-seq.
However, there are much fewer regions that a tag can map to, which leads to a lot of redundant reads.
I don't think only single read should be kept if redundant ones exist.. However, I also think use a maximum number (for example, 5) is also arbitrary. (If there's a distribution model, it would be more reasonable) I saw several threads about how to deal with redundant reads, but didn't find anyone solve it. Does anyone have any idea about that?