We have two Input samples (not IP samples) of MeDIP-Seq analyzed by FastQC. One of Input samples has warning Per sequence GC content (fig1), and the other has failed Per sequence GC content (fig2). Our human mesenchymal stem cells (MSCs) data are 100 bp paired-end reads sequenced by Illumina HiSeq 2000. Do you know what possible problems with our Input samples? Many thanks.