I am a newbie and I am doing a ChIP-Seq analysis on a small dataset of 6 samples (Wild-type and knockout having 3 replicates each). I ran MACS2 for peak calling but the number of peaks in each replicate is very different. For example, WT-Rep1 has 1500 peaks and WT-Rep2 has only 34 peaks. Why is there such a variation ? Did I do something wrong or is the data bad ?