I am merging BAM files corresponding to several replicate experiments into one large BAM file. The resulting file is really large (400 Gb). I was using the "cat" command, and at some point connection to the server broke, so it could be that the end of the BAM file is a bit damaged (e.g. not all parts of the individual BAM files which I was merging are included in the final BAM file). Is it a problem? That is, for the biological analysis it should not be a problem if a small portion of reads is missing. But will it affect the structure of the binary structure of the BAM bile in such a way that it is unusable?