Job: Senior Bioinformatician - Translational Genomics of Cancer
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4.7 years ago by
United Kingdom
Recruit230 wrote:

Senior Bioinformatician - Translational Genomics of Cancer

Salary range: £31033 to £39142per annum plus excellent benefits.

Highly motivated Software Developer/Bioinformatician to join a new international collaboration to create a cancer organoid biobank.

An exciting IT opportunity has become available at the Wellcome Trust Sanger Institute as part of an international effort to generate a large cancer organoid biobank. The aim of this project is to develop cancer organoid models that allow basic biological questions to be addressed, more rapid and accurate drug testing, and influence the treatment options on an individual patient basis.

The successful candidate will join a large multi-disciplinary team and be tasked with developing the IT infrastructure for this important venture. The role will involve working closely with scientific and IT staff within the Cancer Programme to develop and implement novel analysis strategies and sample tracking systems to support this study. In addition, the role will involve improving existing algorithms and developing new database systems to hold clinical data.

We are looking for an individual who enjoys working in a multi-disciplinary team environment to help solve complex IT issues which will ultimately aid our understanding of cancer.

Essential Skills

  • Good degree in Bioinformatics or Computer Science with a scientific background
  • Software development skills in one of Perl, Python, Java or C/C++
  • ORACLE/MySQL databases
  • Enjoy working as part of a team

Ideal Skills

  • Experience of statistical analysis in bioinformatics
  • Experience of handling Next Generation sequencing data
  • LSF or Open Grid scheduling software
  • Experience of workflow management IT systems
  • Experience working, developing and compiling software tools in a UNIX/LINUX environment.
  • Experience of working in an Agile Software Development Group
  • Web development using Perl, Java, HTML(5), CSS, JavaScript
  • Background in cancer genetics
  • Excellent communication skills

Other information

The Wellcome Trust Sanger Institute operates at the forefront of genomics, sequencing and analyses targeting a wide range of genomes from single cell pathogens to higher vertebrates, with an emphasis on genomes relevant to human medicine and welfare. 

The Cancer Genome Project at the Institute has led the way in the systematic analysis of cancer genomes by using the human genome sequence and high throughput mutation detection techniques to identify somatically acquired sequence variants/mutations and hence identify genes critical in the development of human cancers (

The IT group has developed a suite of algorithms to analyse genetic variation in cancer genome data. This includes software to detect tumour genetic variation (e.g. single-base substitutions, structural rearrangements, copy number changes) and the ability to annotate the resulting variants and mine the data for interesting patterns and signatures.

Our Benefits include: Defined Benefit Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Nursery and 25 days Annual Leave plus Bank Holidays. We also have a gym, two cafes, a nursery, dining facilities, and a free campus Bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Please include a covering letter and CV with your application. 

Please state your current salary in the covering letter.

Closing date: 9th March 2016

Please apply via our website: 

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