I have some queries on coverage

Question

[bioinforesearchquestions]

Dear all,

I am going to analyze whole genome sequence (WGS) data of Human sample. I need some clarifications on following terminologies.

1. what is coverage and depth?
2. I have seen people use WGS with expected coverage 30X. Why specifically 30X?
3. How to see my WGS coverage information?
4. Is there any tools to detect the coverage information?
5. Does expected coverage changes for RNAseq and DNASeq?
6. What is the relationship between SNP and coverage?

[venu]

Possible answer for all your questions - What Is The Sequencing 'Depth' ?

[bioinforesearchquestions]

Thanks Venu for the link. I will go through the link