Getting the function of genes based on gene names
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8.1 years ago

I have a list of gene names and I want to know the function of each gene. I tried using the Biomart website but couldn't find a list with gene function. For instance, is it possible to get the CC, MF, and BP GO terms from that website?

genome • 8.2k views
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8.1 years ago
Antoine ▴ 10

From Biomart, you can easily obtain the GO CC, MF and BP you are looking for:

  1. Choose Ensembl database 83 for example
  2. Choose your organism (S. cerevisiae for example)
  3. OPTIONAL : If you want info on a subset of genes only : click on FILTER and add your gene list in the Input external references ID list textbox
  4. Click on ATTRIBUTES then EXTERNAL
  5. Tick the box for the go term
  6. Click on result at the top of the page to visualize or download them!

Example : http://www.ensembl.org/biomart/martview/73fed257731b73cebf31e71a3e933b2d

edit : Optional point added as suggested by Emily_Ensembl

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If you're not familiar with BioMart, you could take a look at the video tutorial.

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You should also probably add in step 2B: filter by your list of gene names.

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8.1 years ago
GenoMax 141k

Here are two site1 site2.

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8.1 years ago

You can try Enrichr, an online gene enrichment tool which features many databases.

Just copy&paste the list of gene symbols, and then select the enrichment dataset you prefer. In your case I would look at the pathways and ontologies.

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