Job:Computational Biologist and Software Engineering Positions at Intellia Tx (Cambridge, MA)
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6.7 years ago

Two positions are currently available at Intellia Therapeutics in Cambridge, MA to work on developing CRISPR/Cas9 based human therapeutics.

COMPANY: The development of CRISPR/Cas9 gene editing technology opens a new frontier in biomedical research and clinical intervention. Adapted from a natural cellular process, CRISPR/Cas9 permits the editing of any gene in any organism with unprecedented simplicity and flexibility. Intellia was founded in 2014 by Caribou Biosciences and Atlas Venture, along with a consortium of leading scientists who have helped define the space. Intellia Therapeutics holds exclusive access to a broad intellectual property portfolio covering the application of CRISPR/Cas9 technology for human therapeutic use.

Title: Computational Biologist

Job Location: Cambridge, MA


SUMMARY: Intellia Therapeutics is seeking a computational biologist/bioinformatician to support the development of CRISPR/Cas9 based therapeutics. This position is an opportunity to contribute to diverse aspects Intellia's bioinformatics platform from the building pipelines for processing NGS data to analyzing downstream data.

GENERAL RESPONSIBILITIES: Develop and support NGS pipelines using commonly utilized tools (BWA, bowtie, samtools, etc) Apply rigorous statistical methods for testing hypotheses on processed data Implement and optimize databases and data storage methods (MySQL) Work with scientists to develop computational methods and tools to support new assays and implement data analyses Create scientifically rigorous visualizations, communications, and presentations of results

REQUIRED SKILLS: Demonstrated ability to write elegant and clean code in R, Python, Perl, or C++ Experience processing and analyzing biological data, specifically sequencing data Familiarity with Linux and shell scripting/bash

QUALIFICATIONS: BS/MS in Bioinformatics with at least 2 years of relevant experience or recent Ph.D. in Computational Biology/Bioinformatics or related field

Title: Software Engineer

Job Location: Cambridge, MA


SUMMARY: Intellia Therapeutics is seeking an experienced software engineer to support the development of CRISPR/Cas9 based therapeutics. You will work to develop a web based platform to expose the results of next-generation sequencing pipelines and R/python based tools for experimental design. This role will require blending experiences in cloud computing, software architecture, database design and maintenance, programming, and software deployment as well as interfacing with computational biologists and biologists to successfully build software which will be critical to developing CRISPR/Cas9 therapeutics.

GENERAL RESPONSIBILITIES: Lead the development of a web based software platform to expose analyses and tools Work closely with the bioinformatics team to implement and deploy work flows and pipelines for handling NGS data Work with scientists to develop and maintain software tools to meet their needs, as required Implement, support, and optimize database solutions Support screening and sequencing through the development of tools to automate processes and work flows, store data, and track samples (LIMS experience preferred)

REQUIRED SKILLS: Demonstrated experience designing, coding, and deploying software Previous experience in the life sciences, working with biological data is preferred Demonstrated full stack web development experience, preferably using the cloud

QUALIFICATIONS: BS or MS in bioinformatics, computer science, or engineering with 4+ years of experience

genome gene editing R ngs Job • 2.1k views

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