have VCf file which contain 1500 SNPs. Due to computational limitation , it is not possible for generating Haplotypes using PHASE program.
What if I break this VCF file into 5 separate VCF files and run the PHASE program individually and later on merging all the haplotype 2gether.
Is that a good idea or i just concentrate on SNPs which are present in the coding region of the genes.
Thanks in advance