dbSNP for recombination mapping
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8.0 years ago
jmckow1 • 0

dbSNPs are databases of common SNPs used to filter out differences due to normal allele variation. Many VCF callers use these files as input. I want to use a dbSNP list to "highlight" known SNPs in some genomes I have had sequenced. Then, hopefully, I can use these "SNP markers" to track recombination events that have happened among some related lines I am studying. A problem I am having with this is dbSNP vcfs seem to have a different format than normal VCFs, so they are not directly comparable. If anyone has done something similar, has advice, or criticisms, I would be very greatfull to have a discussion. Thank You.

snp dbsnp vcf mapping mutation • 1.4k views
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