Question: cytokine data analysis
1
gravatar for elmira b
2.9 years ago by
elmira b40
United States
elmira b40 wrote:

Hi,

I would like to compare cytokine levels of four groups of mice with different treatments. There are four to six mice in each treatment group, so the sample size is not large. The standard deviation of most cytokine levels in each treatment group are much larger than their mean.

Also, there are many zero in data set( very low cytokine levels).

What type of tests should I use to compare cytokine levels in different treatment groups?

Any help is greatly appreciated.

ADD COMMENTlink modified 2.9 years ago by Ronald Rodriguez20 • written 2.9 years ago by elmira b40
1
gravatar for elmira b
2.9 years ago by
elmira b40
United States
elmira b40 wrote:

Mann-whiteny test can be used as a non-parametric test to compare the median of two independent groups (samples do not follow normal distribution)

ADD COMMENTlink modified 2.9 years ago • written 2.9 years ago by elmira b40
1
gravatar for Ronald Rodriguez
2.9 years ago by
Ronald Rodriguez20 wrote:

Due to non-parametric nature of the data I would do Mann-Whitney analysis. This is the non-parametric version of a t-test.

ADD COMMENTlink written 2.9 years ago by Ronald Rodriguez20
0
gravatar for ksi216
2.9 years ago by
ksi21650
ksi21650 wrote:

the standard T test ? are you familiar with it ?

ADD COMMENTlink written 2.9 years ago by ksi21650

Thanks for the response but the standard t-test is for the data with normal distribution.

ADD REPLYlink written 2.9 years ago by elmira b40
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