Hi, Firstly, I am a Computer Science Engineer and a newbie in Bioinformatics.
I have Human mutation data in the following format: UniProt ID, Position, Original Amino Acid, New Amino Acid
I am trying to match this with ExAC data which contains: ENSEMBL Transcript ID, ..., CDS_Start, CDS_End, number of coding base pairs, ... etc
I have the UniProtKB ID to ENSEMBL Transcript ID mapping from one of the sites. But I am unable to map the positions.
How do I convert Protein Position to Transcript's CDS_start and CDS_end (beginning and end of Transcript's coding sequence positions?
I request your help.
Thank you, Rashmi