Question: Must know algorithms before attending a bioinformatics interview
3
gravatar for Prakki Rama
18 months ago by
Prakki Rama2.0k
Singapore
Prakki Rama2.0k wrote:

Hi everyone,

I would like to know the list of most important algorithms that one need to know before attending a bioinformatics interview. Some bioinformatics positions might not require to work with algorithms but still could I have a list for the reference.

Some algo I think very important are :

1) Alignment tool algorithms such as BLAST, BLAT etc.

2) NGS assembly tool algorithms such as velvet, trinity, ABySS etc.

3) Mapping tool algorithms such as bowtie, bwa etc.

Thank you

ADD COMMENTlink modified 18 months ago by igor4.7k • written 18 months ago by Prakki Rama2.0k
5
gravatar for Antonio R. Franco
18 months ago by
Spain. Universidad de Córdoba
Antonio R. Franco3.4k wrote:

Bayesian statistics for studying gen differential expression and the like

ADD COMMENTlink written 18 months ago by Antonio R. Franco3.4k

It seems you are referring to a concept. But, anyway it is also beneficial to have knowledge on this I think. Thank you.

ADD REPLYlink written 18 months ago by Prakki Rama2.0k

You should add to the list the concept of lineal models (regression and the like) as well. They are used a lot in differential expression analysis

ADD REPLYlink written 18 months ago by Antonio R. Franco3.4k
5
gravatar for igor
18 months ago by
igor4.7k
United States
igor4.7k wrote:

It really depends on what sort of bioinformatics position it is. I would say knowing which tools exist and how they differ and how they work together is far more important than algorithms. I met too many people who know theory very well, but can't generate usable results from the raw data.

ADD COMMENTlink modified 18 months ago • written 18 months ago by igor4.7k
2

Agree completely. Unless the position will involve algorithm and method development, knowing how to use tools is probably more important. Outside of the requisite intro to comp bio coursework, I've never had to implement S-W or N-W for any purpose.

ADD REPLYlink written 18 months ago by fanli.gcb610

Very much true. Thank you.

ADD REPLYlink written 18 months ago by Prakki Rama2.0k
4
gravatar for tiago211287
18 months ago by
tiago211287790
Brazil
tiago211287790 wrote:

Smith–Waterman algorithm

Needleman–Wunsch algorithm

ADD COMMENTlink written 18 months ago by tiago211287790
2

Yup. First and foremost to learn. Thank you.

ADD REPLYlink written 18 months ago by Prakki Rama2.0k
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