So I have hundreds ensemble gene transcripts which needs to be converted to NCBI transcripts. I am worried about their being position changes in known mutations. I think one of reasons for this change is to have consecutive exons numbering (1,2,3 etc) instead of (1b,2,3,5) that is found in ensembl.
Gene Transcript Location Position Type Nuc Change AA Change Nuc Name AA Name
A ENST0001 exon 1 69aa c G-->C A-->P(150) c.448G>C p.Ala150Pro
This is roughly what the file looks like before conversion. I think between the formats the Position (AA or nucleotide) will change as will the Nuc Name. * denotes likely area's of change.
Any help would be appreciated