Question: Duplicates in Whole Exome Sequence Data
1
gravatar for haiying.kong
3.9 years ago by
haiying.kong300
Germany
haiying.kong300 wrote:

After alignment with BWA, I used Picard tools to treat duplicates and some other stuff. Our data is whole exome sequence data. Should I remove duplicates with Picard tools, or just mark duplicates so that later software could take care for the duplicates?

whole exome sequence data • 1.2k views
ADD COMMENTlink modified 3.9 years ago by DG7.1k • written 3.9 years ago by haiying.kong300
1
gravatar for DG
3.9 years ago by
DG7.1k
DG7.1k wrote:

Just MarkDuplicates with Picard, there is no need to remove them. Downstream tools are designed to handle them appropriately.

ADD COMMENTlink written 3.9 years ago by DG7.1k
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