I just started my PhD in bioinformatics and specifically alternative splicing using RNA-seq, my background is computer science. I have two big issues at the moment:
- Understanding specific graphs and results in papers
- There are way many gene, isoform, function, cancer names ...
It's really hard to understand papers at the moment and I need to google many things ... I appreciate if you tell me how I can resolve those issues. I have some very basic questions like:
What is novel isoform?
What's the difference between novel transcripts and reference like transcripts?
I think there is no 'one-spot' solution for this (It would be great if anyone provides one). Google the term you don't understand & do not hesitate to reach wikipedia. If you don't understand any context in any of the papers you are reading, post it here, people here are very helpful.
Some useful links
Do you have any biology background?
If not, you might need a crash course. Basic lectures about gene structure, textbooks etc.