Dear Bioinfo Geeks,
I have obtained CLIP-Seq read coverage, which is mostly sequestered in 3’ UTR with relatively much lesser density in the CDS and 5’ UTR (Example). This scenario is true for almost all genes I looked. I am struggling to find a way to represent this pattern for all genes in one figure, which can explain that compared to 3’ UTR, the read density in other regions is lower. Given every gene has different count and lengths of 5' and 3'UTR and CDS, its difficult to adjust all to the same scale. I found some papers, where they used binned density, but I am not able to understand the basic steps to do so. Could some body please help.