Entering edit mode
7.0 years ago
Pranavathiyani G ▴ 330
I have a list of genes, which are possibly cancer causing genes, how can i classify them as oncogene or tumor suppressor gene? Based on what, genes can be classified as oncogene and tumor suppressor gene?
I would add the 20/20 rule introduced by Vogelstein in 2013, which I think was the first formal definition of a rule to determine tumor suppressors and oncogenes.