Question: What training do you think a computer scientist should do to move into the bioinformatics field?
0
gravatar for Lucy
3.3 years ago by
Lucy0
Lucy0 wrote:

Hello,

What training do you think a computer scientist should do to move into the bioinformatics field?

I am a post-doc in Computer Science (Data analysis & Machine learning) and my project is related to clinical data and expression data analysis. I'm trying to identify some training courses which I could do to improve my skills. My aim is to be able to interpret my analysis in biology context. I've been looking at some courses in bioinformatics and they seem to be targeted for biologists rather than computer science. Do you have any suggestion for me? Note that, I'm based in UK, so would appreciate if the training you recommend is provided here.

Appreciate your thoughts!

Lucy

ADD COMMENTlink modified 3.3 years ago by ivivek_ngs4.8k • written 3.3 years ago by Lucy0

Start by reading Campbell Biology and Alberts Molecular Biology of the Cell (in this order).

ADD REPLYlink written 3.3 years ago by 5heikki8.5k

I've got Campbell book here on my desk :D

ADD REPLYlink written 3.3 years ago by Lucy0
3
gravatar for Dan Gaston
3.3 years ago by
Dan Gaston7.1k
Canada
Dan Gaston7.1k wrote:

Focus on the biology. Given your CS skills you can do some online bioinformatics courses that are higher level just to learn the algorithms (if you don't know them already), major parameters and how they work, etc. But the biggest thing to do is learn the biology. If possible sit in on some undergraduate lectures, grad level seminar series, etc. Go to departmental seminars. If you don't understand the biology you will consistently do uninformed analyses.

ADD COMMENTlink written 3.3 years ago by Dan Gaston7.1k
1

Focus on the biology.

especially on molecular genetics and cellular biology; you should also know about the standard methods used in molecular biology and their shortcomings.

ADD REPLYlink modified 3.3 years ago • written 3.3 years ago by piet1.7k

Absolutely! I don't do wet work, but I try and know details of most of the wet work whose data I do analysis on. I need to know the biology of the experimental systems to make good choices in my analysis, and where sources of variability and noise might come from.

ADD REPLYlink written 3.3 years ago by Dan Gaston7.1k

I agree. Whenever I do analysis I need to know how my data is generate and where it comes from. I'm going to sit in some introduction courses this autumn.

ADD REPLYlink written 3.3 years ago by Lucy0
2
gravatar for Dataman
3.3 years ago by
Dataman310
Finland
Dataman310 wrote:

Nowadays, there are many good quality online courses (MOOCs) available for free and also you can get a certificate if you pay a fee. These can help you start or give you ideas where to go next. For instance:

On Coursera:
Bioinformatics Specialization
Genomic data science specialization
Systems Biology and Biotechnology Specialization

On EdX:
Data Analysis for Life Sciences 1: Statistics and R
Data Analysis for Life Sciences 2: Introduction to Linear Models and Matrix Algebra
Data Analysis for Life Sciences 3: Statistical Inference and Modeling for High-throughput Experiments
Case Studies in Functional Genomics

I will keep updating this list. Hope this is helpful.

[Update-1]:
Here is a list of articles dubbed "guide to genomics" by their collectors worthy of reading.

ADD COMMENTlink modified 3.2 years ago • written 3.3 years ago by Dataman310

Thanks for the list. Seems like a good way to start.

ADD REPLYlink written 3.3 years ago by Lucy0
0
gravatar for ivivek_ngs
3.3 years ago by
ivivek_ngs4.8k
Seattle,WA, USA
ivivek_ngs4.8k wrote:

Apart from wonderful answers I would ad up some recurrent threads of the forum

  1. Bioinformatics And Computer Science

  2. How Did You Learn Good Practice In Bioinformatics/Computational Biology?

  3. Getting into Bioinformatics

  4. Also the quora link might be useful

Good luck!

ADD COMMENTlink written 3.3 years ago by ivivek_ngs4.8k
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