Question: ENCODE bam file hg19 v19
0
gravatar for li487
3.3 years ago by
li4870
li4870 wrote:

I found that in the ENCODE database, hg19 v19 contain two bam files for each biological replicate, and they are different bam file, so what is the difference between the two bam file?

Here is an example: https://www.encodeproject.org/experiments/ENCSR109IQO/ Both ENCFF353VRV and ENCFF042VVP belong the hg19 alignment biological replicate 2.

bam encode assembly • 1.0k views
ADD COMMENTlink modified 3.3 years ago by Emily_Ensembl19k • written 3.3 years ago by li4870
0
gravatar for genomax
3.3 years ago by
genomax73k
United States
genomax73k wrote:

As indicated on the page you linked they are isogenic replicates. Here is the definition from ENCODE project.

Isogenic replication - Biological replication. Two replicates from biosamples derived from the same human donor or model organism strain. These biosamples have been treated separately (i.e. two growths, two separate knockdowns, or two different excisions).

ADD COMMENTlink modified 3.3 years ago • written 3.3 years ago by genomax73k
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