Job:Associate Computational Scientist (Mass Spectrometry)- Intellia Therapeutics, Cambridge, MA, USA
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6.4 years ago

Title: Associate Computational Scientist

Job Location: Cambridge, MA


COMPANY: The development of CRISPR/Cas9 gene editing technology opens a new frontier in biomedical research and clinical intervention. Adapted from a natural cellular process, CRISPR/Cas9 permits the editing of any gene in any organism with unprecedented simplicity and flexibility. Intellia was founded in 2014 by Caribou Biosciences and Atlas Venture, along with a consortium of leading scientists who have helped define the space. Intellia Therapeutics holds exclusive access to a broad intellectual property portfolio covering the application of CRISPR/Cas9 technology for human therapeutic use.

SUMMARY: Intellia Therapeutics is seeking a computational biologist with a strong focus in the analysis of mass spectrometry data to support the development of CRISPR/Cas9 based therapeutics. This position will require working cross-functionally with chemistry and biology to develop pipelines, databases, and analyses to support the use of mass spectrometry data.

GENERAL RESPONSIBILITIES: Develop, deploy, and support pipelines to process various types of data being generated using mass spectrometry Build and support a relational database which stores experimental data and processed results Conduct analyses of processed data using rigorous statistics and display results in visualizations

REQUIRED SKILLS: Preferably, experienced with Thermo raw mass spectral data handling including scripting pipelines, automated data base searching, and parameter file building Experience using multiple analyses programs (Proteome Discoverer, PepFinder, ProMass, TPP, MaxQuant, etc) Strong understanding of statistics applied to the analysis of biological and mass spectral data Ability to design, deploy, and support relational databases including using SQL Experience handling data from multiple sample types including protein characterization, proteomics, oligonucleotides, and lipids Demonstrated programming experience in languages such as bash, Python, Matlab, R, or Perl

QUALIFICATIONS: BS/MS or equivalent with at least 3 years of industry experience or PhD with 1 year of industry of experience


CRISPR/Cas9 mass spec Job • 1.9k views

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