Computational Research Topics in Transcriptional Gene Regulation

Question

[Sama]

I want to find a research topic in Transcriptional Gene Regulation. My background is Computer Science so I am not familiar with general important topics in this area. I guess one of the problems is Predicting Enhancer Target Gens. What computational problems exist related to Transcriptional Gene Regulation?

Answer 1

[natasha.sernova]

Dear Sama,

What organisms would you like to study?

I've looked at your previous posts - they are about bacteria, prokaryotes.

But enhancers can be encountered in eukaryotes.

Take a look at this review.

http://www.cse.cuhk.edu.hk/~kevinyip/papers/EnhancerReview_CBBGR2015.pdf

avd this paper:

http://nar.oxfordjournals.org/content/early/2014/11/05/nar.gku1058.full

You will have to change the topic of your research. And many tools for enhancer-search have already existed.

[Sama]

Thank you. I have changed my subject and I do not study bacteria anymore.