How to conduct survival analysis on multiple genes and set p-value conditions for plotting?
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7.8 years ago
jzhou ▴ 20

Hi All, So I have been doing some survival analysis using the extremely helpful tutorial Survival analysis of TCGA patients integrating gene expression (RNASeq) data, but being new to R I was wondering if anyone could help me with some changes that I'd like to make. Instead of just choosing one gene to check the p-value and plot, I instead want to write a code that would divide the genes into up and down-regulated, and create a loop or something equivalent that does survival analysis on and extracts the p-value for every gene and then lists the top 20 up-regulated and top 20 down-regulated genes after it is done. I've tried a lot of code but I'm afraid that I'm really not good at this and any help to achieve my goal would be hugely appreciated! Thanks so much

RNA-Seq survival analysis R • 2.5k views
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