Entering edit mode
7.7 years ago
fire_water
▴
80
Hello. I have some VCF files which I will be working with. Today I came across a tool named VCF Tools and it seems like it might be useful. However, before I download and install it, I was wondering if it will be able to answer all of the following case scenarios:
Case Scenario 1:
- All known (have an RS id) polymorphic positions for sample IDs starting with P0048* with AF<0.10.
Case Scenario 2:
- All unknown polymorphic positions for sample IDs starting with P0048* with AF<0.10.
Case Scenario 3:
- All known (have an RS id) polymorphic positions for sample IDs starting with P0048* with AF<0.10. Report the genotypes for all individuals in the family that have a coverage for those positions greater than 20 (i.e. DP >20) for individuals with DP <20 replace genotype with ./.
Thanks!
