Question: How to compute the average distances between groups of taxa with Mega?

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cloverchicken •

**0**wrote:I have pyrosequencing data set of a nuclear gene, up to 36000 sequences. I tried to compute the average distances between groups of taxa with Mega but when I defined sequence groups, Mega stopped responding? Can anyone help?

Thank you.

Thank you so much for the help. So it seems like Mega only works with 800 sequences. We decided to prepare a python code for the calculation anyway. Have a nice day.

0Any chance you have solved this problem with a python script? I am facing the same issue now where I need to calculate an average p-distance without MEGA and am not sure how to go about it.

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