Hi,
I am new to bioinformatics, I have microarray data that platform is [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array. I want to normalize expression for each gene relative to the expression of the five reference genes (ACTB [the gene encoding b-actin], GAPDH, GUS, RPLPO, and TFRC) in R. Is there any package that ı can use.
Thank you very much
Thank you very much for your helping