MIR name nomenclature
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7.7 years ago
sacha ★ 2.4k

I don't understand the naming of MIR. what the difference between MIR1302-11 and MIR1302-10 ?

in refGene, it looks exactly same :

1367    chr15   102500661       102500799       102500799       102500799       1       MIR1302-10
1367    chr15   102500661       102500799       102500799       102500799       1       MIR1302-11
MIR • 1.7k views
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http://www.mirbase.org/help/nomenclature.shtml

Distinct precursor sequences and genomic loci that express identical mature sequences get names of the form hsa-mir-121-1 and hsa-mir-121-2

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I don't understand the meaning. Distinct genes locus with same transcript ?
So why refgene coordinate are same?

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One (or both) of the entries above seem to be incorrect.

From NCBI

http://www.ncbi.nlm.nih.gov/gene/100422834
http://www.ncbi.nlm.nih.gov/gene/100422919

From GeneCards

Genomic Location for MIR1302-10 Gene
Chromosome:15
Start:101,960,459 bp from pterEnd:101,960,596 bp from pter
Size:138 basesOrientation:Minus strand

Genomic Location for MIR1302-11 Gene
Chromosome:19
Start:71,973 bp from pterEnd:72,110 bp from pter
Size:138 basesOrientation:Plus strand
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