estimate genome coverage
Hi, I ran KmerGenie and I got the best Kmer and the estimated genome size. How do I get the estimated genome coverage?
Thank you in advance.
Or more broadly and easily...
C = R x L / G
Where C is physical coverage, R is the total number of reads, L is (average) read length, and G is the genome size.
So for example, if you have a 100 Mbp genome and an Illumina library with 10 M reads of length 150 bp, the coverage of the genome is 15X (10,000,000 * 150 bp / 100,000,000 bp).
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