Question: Quite low mapping efficient for single-cell methylation sequencing data
gravatar for Shicheng Guo
3.5 years ago by
Shicheng Guo8.0k
Shicheng Guo8.0k wrote:

Hi All,

Taking SRR2876110 as the example (single-cell bisulfite sequencing for ES), any one have pay attention to the low mapping efficient? In my own alignment with bismark, the mapping efficient is only 5-10%. Really don't understand why the mapping ratio is so low?


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