Question: Looking for big data of SNPs in Alzheimer's disease
0
gravatar for Alexandra
2.9 years ago by
Alexandra0
Germany
Alexandra0 wrote:

Hi,

I'm currently in an internship in a research group for Alzheimer's disease. I have to look for some big data to download with SNPs associated to Alzheimer. Do you have any idea, where I can find such data? I think dbSNP could be a good database and you can download some files via ftp, but I'm not sure, if there are files with SNPs associated with Alzheimer. I downloaded the file from snp4disease, but there are only ~2900 entries. For our research, I had to look for studies with many patients, but I'm not sure where to look for it. If you know, where I can find such big data (and to download it), please let me know. I need the information to calculate a linkage disequilibrium.

Thanks.

big data snp alzheimer • 1.2k views
ADD COMMENTlink written 2.9 years ago by Alexandra0

Have a look at Open Targets Platform. This post gives more details on AD. The main entities there are genes (or targets) and diseases (i.e. AD) and their association are available for download as well as the evidence (e.g. genetic variants from GWAS, etc) used to suggest the association.

ADD REPLYlink modified 2.5 years ago • written 2.9 years ago by Denise - Open Targets5.0k

Thanks. I will visit this platform and download the data. Maybe it could be helpful.

ADD REPLYlink written 2.9 years ago by Alexandra0
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