Question: comparing log2 of allelic-imbalance (converted to Z-score) of different cancer types
0
gravatar for Mike Vermeulen
3.2 years ago by
Mike Vermeulen0 wrote:

Currently I have the allele-specific expression data on 12 different cancer types from TCGA.

I've organized them into matrices that consist of log2(alleleA_readcounts/alleleB_readcounts) for each gene for each patient I've also converted this into a Z-score matrix (Z-score across each gene,) but I'm not sure if this is necessary.

There is also a bunch of other data available such as a matrix of p_values of the ASE, clinical data ect.

I'm now trying to characterize/cluster the cancer types based on this data but I'm unsure how I'll do this. I'm in the process of developing an algorithm but this may take a while.

Does anyone have any insight or ideas as to where I could go next?

rna-seq matlab ase z-score matrix • 882 views
ADD COMMENTlink written 3.2 years ago by Mike Vermeulen0
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1639 users visited in the last hour