Question: Normalization necessary for TCGA 450K data?
0
gravatar for mbk0asis
4.2 years ago by
mbk0asis570
Korea, Republic Of
mbk0asis570 wrote:

Hi, all.

I just downloaded 450K methylation data from TCGA and found that the data contain control probes for something.

I'm sure, but I'm guessing they are for normalization.

So, do I need to normalize the data using some tools, or can I just use it for analysis?

If I have to do the former one, which tool should I use?

Thank you!

normalization 450k • 1.5k views
ADD COMMENTlink modified 4.2 years ago by igor11k • written 4.2 years ago by mbk0asis570
0
gravatar for igor
4.2 years ago by
igor11k
United States
igor11k wrote:

It depends on what format the data is in. You can download different files. Did you download the processed files (normalized) or the raw IDATs (not normalized)?

ADD COMMENTlink modified 4.2 years ago • written 4.2 years ago by igor11k
1

I downloaded them from here. I'm not sure if they are normalized or not because there is no indication on that page.

ADD REPLYlink modified 4.2 years ago • written 4.2 years ago by mbk0asis570
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1684 users visited in the last hour