Question: Difference between Cosmic Annotation from VEP and directly from COSMIC VCF.
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always_learning • 1.0k wrote:
Hi All,
I am trying to annotate few VCF files from VEP with Cosmic ID's and same VCF is being annotated using Cosmic VCF's. For some reasons I am getting I am more Cosmic hits from VEP annotation compare to the direct annotation from Cosmic VCF files.
If some one else has observed same trend ? How VEP is picking up cosmic annotations ? If sources are same then why I am getting different result from both.
Thanks