Difference between Cosmic Annotation from VEP and directly from COSMIC VCF.
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4.7 years ago
always_learning ★ 1.1k

Hi All,

I am trying to annotate few VCF files from VEP with Cosmic ID's and same VCF is being annotated using Cosmic VCF's. For some reasons I am getting I am more Cosmic hits from VEP annotation compare to the direct annotation from Cosmic VCF files.

If some one else has observed same trend ? How VEP is picking up cosmic annotations ? If sources are same then why I am getting different result from both.

Thanks

VEP Annotation • 2.2k views
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