Question: Negative and positive linkage disequilibrium
0
gravatar for fatima
20 months ago by
fatima10
fatima10 wrote:

Hello everyone,

Could you explain me what is exactly the meaning of Negative and positive LD which mentioned in Plink "-flip-scan"?

The result fo the "--flip-scan" is plink.fipscan and I have nan for all elements of R_NEG column. What is the problem for that?

Thank you.

ld plink gwas linkage • 678 views
ADD COMMENTlink modified 4 months ago by seta990 • written 20 months ago by fatima10
0
gravatar for seta
4 months ago by
seta990
Sweden
seta990 wrote:

Although it's late, as far as I know, under linkage disequilibrium, haplotypes do not occur at the frequencies expected when the alleles were independent. Positive linkage disequilibrium exists when two alleles occur together on the same haplotype more often than expected, and negative LD exists when alleles occur together on the same haplotype less often than expected.

ADD COMMENTlink written 4 months ago by seta990
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