Postdoctoral Researcher - Molecular Biologist
£30,750 - £37,750
Job Type: Postdoctoral Researcher
Contract length: 36 months
Closing date: 18 November 2016
The primary aim will be to research and develop new experimental approaches for uncovering the structure and genetic diversity of complex crop genomes. The post will provide an interface between the Earlham's high-throughput genomics labs (run by the Platforms and Pipelines Group and the bioinformaticians in the Hall lab.
The post holder will have a broad understanding of molecular biology techniques, and experience of researching, developing and optimising complex molecular biology protocols. Candidates should have a publication record to demonstrate this, along with experience in oral research presentations.
To be considered for this post, candidates should hold a PhD in molecular biology, or MSc/BSc with significant experience working in a high-throughput genomics centre with a focus on next-generation sequencing protocols, and possess the following skills and experience
The Hall lab has recently moved to the Earlham Institute where they are investigating the genetic and epigenetic diversity of bread wheat. The lab also works on the function and underlying mechanism of the circadian clock in model and crop species.
- Develop and optimise new lab protocols for genome-wide analysis of DNA and histone methylation in complex genomes
- Scale up and automate protocols to allow the population-scale studies of epigenetics
- Visit, isolate and ship DNA and RNA samples from field trials in India and Mexico. Help support and coordinate local staff.
- Learn, develop and optimise methods for scaffolding short reads using 10X Genomics and HiC data for de novo genome assembly
- Develop and test new exome capture pipelines, working and coordinating with manufacturers
