The Immunogenetics Clinical Laboratory is part of the Children's Hospital of Philadelphia Division of Genomics Diagnostics and the Department of Pathology & Laboratory Medicine. The Immunogenetics Clinical Laboratory serves the Solid Organ and Stem Cell Transplant Programs at the Children's Hospital of Philadelphia, and additionally, provides transplant support and testing for its outreach partners. Job Responsibilities
The Immunogenetics Clinical Lab focuses on the role of Histocompatibility (HLA) molecules and of the Major Histocompatibility Complex (MHC) in autoimmunity and transplantation. We are interested in the detailed characterization of the MHC by high throughput DNA sequencing technologies and the identification of polymorphisms important for many HLA-associated diseases and rejection processes in transplantation. The Bioinformatics Scientist will work in a team environment and interact with experts in immunogenetics, bioinformatics, and IT to perform, support, and develop cutting edge clinical diagnostics at CHOP. The responsibilities of the Bioinformatics Scientist include the following.
Required Licenses, Certifications, Registrations
Required Education and Experience
Master’s or PhD degree in Bioinformatics, Computational Biology or closely related fields. Four to five (4-5) years of experience in applied bioinformatics, genomics, and computational work, which can include experience gained from PhD dissertation work. Strong working knowledge or training in advanced biomedical research. Background in Immunology, Histocompatibility, Immunogenetics, and/or HLA experience preferred. Experience with Next-Generation Sequencing (NGS) technologies and NGS data analysis preferred. Demonstrated skills utilizing bioinformatics algorithms, tools and resources, e.g. sequence retrieval, alignment and clustering techniques, expression profiling and protein related analysis, using major databases and data standards in the field. Expertise in nucleic databases both in flat file and relational forms. Fluency in ORACLE/SQL, JAVA, PERL, C++, Python, HTML, XML, PHP, R, Matlab, or other languages. Ability to write and implement complex computer programs and analysis pipelines. Proficiency in UNIX, LINUX, Mac OS X, and Windows operating systems. Ability to independently set up and maintain multiple computer systems including cluster/server/workstation/PC/MAC. Excellent interpersonal skills to interact and communicate with both clinical lab technical staff and research staff. Excellent writing, communication and analytical skills Ability to work independently with minimal guidance while consistently exercising good judgment. Ability to learn new technologies quickly. Ability to work efficiently on multiple projects.
All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.
The Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at The Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).
The Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.
Please visit the CHOP website and apply at: