Question: How to calculate power calculations for 450K methylation array data
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gravatar for shocker8786
2.9 years ago by
shocker87860 wrote:

I'm working on an experimental design in which I need to calculate power calculations for detecting differential methylation across 2 groups using the 450K methylation array. I have experience with Illumina sequence data, but not methylation array data. Is it possible to perform a power calculation without any pre-existing data to get an estimate of the number of samples I need to have for each comparison? Any insights would be greatly appreciated. Thanks!

ADD COMMENTlink modified 2.9 years ago by Neilfws48k • written 2.9 years ago by shocker87860
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gravatar for Neilfws
2.9 years ago by
Neilfws48k
Sydney, Australia
Neilfws48k wrote:

You may find this article useful:

Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation

ADD COMMENTlink written 2.9 years ago by Neilfws48k
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